Molecule

Tadalafil

73 brands of Tadalafil in stock, compared side by side.

Brands of this molecule, with strength, pack size and price
Brand	Strength	Pack	Price	Per unit	Availability
Tadalista Professional As Directed Tablets	As Directed	10 Tablets	$ 76.00	$ 7.60	Out of stock
Tadarise 5 Mg Tablets	5 Mg	30 Tablets	$ 18.00	$ 0.60	In stock
Modula 5 Mg Tablet	5 Mg	10 Tablets	$ 30.00	$ 3.00	In stock
Ttab 5 Mg Tablet 10	5 Mg	10 Tablets	$ 30.00	$ 3.00	In stock
Tafil 5 Mg Tablet 10	5 Mg	10 Tablets	$ 30.00	$ 3.00	In stock
Tadgo 5 Tablet 10	5 Mg	10 Tablets	$ 30.00	$ 3.00	In stock
Tfil 5 Mg Tablet 4	5 Mg	4 Tablets	$ 30.00	$ 7.50	In stock
Mildfil 5 Mg Tablet 10	5 Mg	10 Tablets	$ 30.00	$ 3.00	In stock
Vidalista 5 Mg Tadalafil Tablets	5 Mg	30 Tablets	$ 37.00	$ 1.23	In stock
Cialis 5 Mg Tablets	5 Mg	20 Tablets	$ 340.00	$ 17.00	In stock
Megalis 10 Mg Tablet 4	10 Mg	4 Tablets	$ 20.00	$ 5.00	In stock
Tazzle 10 Mg Tablets	10 Mg	10 Tablets	$ 23.75	$ 2.38	Out of stock
Zydalis 10 Mg Tablet 4	10 Mg	4 Tablets	$ 30.00	$ 7.50	In stock
Zydalis Md 10 Mg Tablet 4	10 Mg	4 Tablets	$ 30.00	$ 7.50	In stock
Upwardz 10 Mg Tablet 4	10 Mg	4 Tablets	$ 30.00	$ 7.50	In stock
Tadgo 10 Mg Tablet 4	10 Mg	4 Tablets	$ 30.00	$ 7.50	In stock
Tfil 10 Mg Tablet 4	10 Mg	4 Tablets	$ 30.00	$ 7.50	In stock
Riseup 10 Mg Tablet 4	10 Mg	4 Tablets	$ 30.00	$ 7.50	In stock
Tadarise 10 Mg Tablets	10 Mg	100 Tablets	$ 34.00	$ 0.34	In stock
Megalis 10 Mg Tablets	10 Mg	4 Tablets	$ 35.90	$ 8.98	In stock
Tastylia 10 Mg Orally Disintegrating Strip	10 Mg	10 Strips	$ 40.00	$ 4.00	In stock
Duraplus Tablet	10 Mg	20 Tablets	$ 48.00	$ 2.40	In stock
Vidalista 10 Mg Tablets	10 Mg	10 Tablets	$ 60.00	$ 6.00	In stock
Tastylia 10 Mg Tablets	10 Mg	100 Tablets	$ 70.00	$ 0.70	In stock
Cialis 10 Mg Tablets	10 Mg	20 Tablets	$ 340.00	$ 17.00	In stock
Tadarise 20 Mg Tablets	20 Mg	100 Tablets	—	—	In stock
Tada 20 Mg Tablets	20 Mg	10 Tablets	$ 2.24	$ 0.22	Out of stock
Forzest 20 Mg Tablets	20 Mg	4 Tablets	$ 2.46	$ 0.62	In stock
Forzest 20 Tablet 7	20 Mg	7 Tablets	$ 2.46	$ 0.35	In stock
Tadarise 20 Mg Oral Jelly	20 Mg	30 Sachets	$ 8.00	$ 0.27	In stock
Megalis 20 Mg Tablet	20 Mg	20 Tablets	$ 20.00	$ 1.00	In stock
Tadacip 20 Mg Tablets	20 Mg	20 Tablets	$ 21.00	$ 1.05	In stock
Vidalista Professional 20 Mg Tablets	20 Mg	30 Tablets	$ 24.00	$ 0.80	In stock
Tazzle 20 Mg Tablets	20 Mg	10 Tablets	$ 24.70	$ 2.47	Out of stock
Tadarise Pro 20 Mg Tablets	20 Mg	30 Tablets	$ 25.00	$ 0.83	In stock
Chocolis 20 Mg Chewable Tablet	20 Mg	30 Tablets	$ 26.00	$ 0.87	In stock
Zydalis Md 20 Mg Tablet 4	20 Mg	4 Tablets	$ 30.00	$ 7.50	In stock
Tadovas 20 Mg Tablet 10	20 Mg	10 Tablets	$ 30.00	$ 3.00	In stock
Tadgo 20 Mg Tablet 4	20 Mg	4 Tablets	$ 30.00	$ 7.50	In stock
Tfil 20 Mg Tablet 4	20 Mg	4 Tablets	$ 30.00	$ 7.50	In stock
Tadarad 20 Mg Tablets	20 Mg	10 Tablets	$ 32.06	$ 3.21	In stock
Tastylia Oral Jelly 20 Mg	20 Mg	28 Sachets	$ 39.00	$ 1.39	In stock
Tadalis Sx 20 Mg Tablets	20 Mg	20 Tablets	$ 41.00	$ 2.05	In stock
Apcalis-sx 20 Mg Oral Jelly	20 Mg	21 Sachets	$ 45.00	$ 2.14	In stock
Carefill 20 Mg Tablets	20 Mg	100 Tablets	$ 50.00	$ 0.50	In stock
Ceebis 20 Mg Tablets	20 Mg	10 Tablets	$ 52.44	$ 5.24	In stock
Tadarise Effervescent 20 Mg Tablets	20 Mg	28 Tablets	$ 63.00	$ 2.25	In stock
Vidalista 20 Mg Tablets	20 Mg	100 Tablets	$ 69.00	$ 0.69	In stock
Abhirise 20 Mg Tadalafil Tablets	20 Mg	100 Tablets	$ 70.00	$ 0.70	In stock
Tadalista Ct 20 Mg Tablets	20 Mg	10 Tablets	$ 76.00	$ 7.60	Out of stock
Super Vidalista Tablets	20 Mg	100 Tablets	$ 80.00	$ 0.80	In stock
Tastylia 20 Mg Disintegrating Strip	20 Mg	60 Strips	$ 109.00	$ 1.82	In stock
Cialis 20 Mg Tablets	20 Mg	20 Tablets	$ 340.00	$ 17.00	In stock
Vidalista 2.5 Mg Tablets	25 Mg	10 Tablets	$ 20.00	$ 2.00	In stock
Tadarise 2.5 Mg Tablets	25 Mg	30 Tablets	$ 21.00	$ 0.70	In stock
Tadaza 10/30 Mg Tablet 4	30 mg	4 Tablets	$ 30.00	$ 7.50	In stock
Vidalista 40 Mg Tablets	40 Mg	30 Tablets	$ 27.00	$ 0.90	In stock
Tadarise Pro 40 Mg Tablets	40 Mg	100 Tablets	$ 33.00	$ 0.33	In stock
Tadarise 40 Mg Tablets	40 Mg	30 Tablets	$ 33.00	$ 1.10	In stock
Extra Super Tadarise Tablets	40 Mg	100 Tablets	$ 40.00	$ 0.40	In stock
Super Tadarise	40 Mg	100 Tablets	$ 50.00	$ 0.50	In stock
Carefill 40 Mg Tablets	40 Mg	100 Tablets	$ 60.00	$ 0.60	In stock
Abhirise 40 Mg Tadalafil Tablets	40 Mg	100 Tablets	$ 66.00	$ 0.66	In stock
Cialis 40 Mg Tablets	40 Mg	20 Tablets	$ 340.00	$ 17.00	In stock
Vidalista 60 Mg Tablets	60 Mg	30 Tablets	$ 30.00	$ 1.00	In stock
Tadarise 60 Mg Tablets	60 Mg	30 Tablets	$ 36.00	$ 1.20	In stock
Cialis 60 Mg Tablets	60 Mg	20 Tablets	$ 340.00	$ 17.00	In stock
Vidalista 80 Mg Tablets	80 Mg	30 Tablets	$ 40.00	$ 1.33	In stock
Abhirise 80 Mg Tablets	80 Mg	100 Tablets	$ 60.00	$ 0.60	In stock
Vidalista Black 80 Mg Tablet	80 Mg	100 Tablets	$ 90.00	$ 0.90	In stock
Sildalist Tablets	100 Mg	30 Tablets	$ 31.00	$ 1.03	In stock
Sildalist Strong 140 Mg Tablets	100 Mg	100 Tablet	$ 45.00	$ 0.45	In stock
Extra Super Vidalista Tablet	100 Mg	100 Tablets	$ 90.00	$ 0.90	In stock

About Tadalafil

Tadalafil is commonly sold under the brand names Cialis and Adcirca.

It is a well-known phosphodiesterase type-5 (PDE-5) inhibitor primarily used to treat erectile dysfunction (ED), benign prostatic hyperplasia (BPH), and pulmonary arterial hypertension (PAH).

Information About Tadalafil

Chemical Structure & Formula: Tadalafil has the molecular formula C22H19N3O4 and belongs to the class of PDE-5 inhibitors that enhance blood flow by relaxing blood vessels.

Discovery & Development

Tadalafil was discovered by GlaxoSmithKline in collaboration with ICOS Corporation in the 1990s. Later, Eli Lilly and Company took over the development and commercialized it under the brand name Cialis.

Approval & Regulatory Status

The FDA approved Tadalafil for erectile dysfunction in 2003 and later for pulmonary arterial hypertension. It is also recognized by EMA and WHO for medical use.

Mode of Action

Tadalafil works by inhibiting the PDE-5 enzyme. This, in turn, increases the levels of a molecule named cGMP (cyclic guanosine monophosphate), which results in the relaxation of smooth muscle in blood vessels.

This leads to increased blood flow to the penile region, aiding in erection. Tadalafil also has other therapeutic uses, including the treatment of benign prostatic hyperplasia (BPH) and pulmonary arterial hypertension (PAH).

Uses of Tadalafil

Primary Uses

Erectile Dysfunction (ED): Tadalafil helps men achieve and maintain an erection. ED, or impotence, is a condition where a man is unable to achieve or maintain an erection firm enough for sexual intercourse. Tadalafil works by relaxing the muscles in the blood vessels of the penis, allowing for increased blood flow, which helps achieve and maintain an erection when combined with sexual stimulation.
Benign Prostatic Hyperplasia (BPH): It improves urinary symptoms related to prostate enlargement. BPH is a non-cancerous enlargement of the prostate gland, which can cause urinary symptoms such as frequent urination, urgency, and difficulty emptying the bladder. Tadalafil helps by relaxing the muscles in the prostate and bladder, improving urine flow and reducing the symptoms associated with BPH. In fact, this is the only drug that has been shown to simultaneously treat ED and BPH in older men.
Pulmonary Arterial Hypertension (PAH): Tadalafil is also approved to treat PAH, a condition characterized by high blood pressure in the arteries of the lungs. By relaxing the blood vessels in the lungs, tadalafil helps improve exercise ability and decrease symptoms like shortness of breath and fatigue associated with PAH.

Off-Label Uses

Raynaud’s Phenomenon: Some studies suggest tadalafil helps in reducing symptoms of this vascular condition.
Altitude Sickness: Research indicates that Tadalafil can provide possible benefits in improving oxygenation at high altitudes.

How Tadalafil Works

Tadalafil inhibits PDE-5, an enzyme that breaks down cGMP, which is responsible for muscle relaxation and enhanced blood flow. By blocking PDE-5, tadalafil maintains sustained cGMP levels, improving blood flow.

The tadalafil 5 mg dose starts to work within 30-60 minutes of consumption.

Factors Affecting Its Effectiveness

Food Intake: Consuming a high-fat meal before taking tadalafil can slow down its absorption, delaying its onset of action. While the medication will still take effect, it may take longer to work compared to when taken on an empty stomach or with a light meal.
Metabolism: The speed at which an individual’s body processes tadalafil affects its duration and potency. Those with a slower metabolism may experience prolonged effects, meaning the medication remains active for a longer period. Conversely, individuals with a faster metabolism may find that the drug’s effects wear off more quickly.
Genetic Variations: Differences in enzyme activity, particularly in how the liver metabolizes tadalafil, can lead to varied responses among individuals. Some people may experience a stronger or longer-lasting effect, while others may find the drug less effective due to genetic factors influencing drug breakdown and absorption.
Alcohol and Drug Interactions: Excessive alcohol consumption can reduce the effectiveness of tadalafil and increase the risk of side effects such as dizziness. Tadalafil can also interact with certain medications, particularly nitrates (used for chest pain) and alpha-blockers (used for high blood pressure or BPH), leading to potentially dangerous drops in blood pressure. Always tell your doctor about any medications you are currently taking.
Heart Health: Since tadalafil affects blood vessels, individuals with heart conditions should be cautious and consult their healthcare provider before using it. It is generally not recommended for people with severe heart problems or those who have had a recent heart attack or stroke.

Common Side Effects of Tadalafil

There can be a few side effects with the tadalafil usage. Always consult your doctor when you feel something is beyond normal.

Mild Side Effects

Headache
Flushing
Nasal congestion
Indigestion
Muscle pain

Moderate to Severe Side Effects

Blurred vision
Sudden hearing loss
Priapism (prolonged erection)
Hypotension (low blood pressure)

When to Seek Medical Help

If you experience any of the following, consult a doctor immediately:

An erection lasting longer than four hours.
Severe chest pain or dizziness.
Sudden loss of vision or hearing.

Available Medicines for Tadalafil

Brand Names

Tadalafil is available under various brand names and generic versions.

Brand Name	Manufacturer	Strengths
Cialis	Eli Lilly	2.5 mg, 5 mg, 10 mg, 20 mg
Adcirca	United Therapeutics	20 mg
Tadaflo	Cipla	10 mg, 20 mg
Forzest	Sun Pharmaceutical Industries Ltd	10 mg, 20 mg
Generic Cialis	Various	5 mg, 10 mg, 20 mg

Tadalafil Dosage & Strengths

Tadalafil is available in various strengths, including 2.5 mg, 5 mg, 10 mg, 20 mg, and higher strengths as required. Always consult your doctor before starting a dosage.

Erectile Dysfunction (ED)

The recommended starting tadalafil dosage for erectile dysfunction is 10 mg, taken as needed. However, your doctor may adjust it based on its effectiveness and your body's response.

Standard dose: 10 mg before sexual activity
Maximum dose of tadalafil in 24 hours: One tablet (10 mg or 20mg)
Effects can last more than 24 hours, so daily use of the 10mg or 20mg tablet is not advised
Requires sexual stimulation to work effectively

Benign Prostate Enlargement

Dosage: Tadalafil 5 mg once daily.
If treating both benign prostate enlargement and erectile dysfunction, the recommended dose remains 5 mg per day.

Pulmonary Hypertension

Standard dosage: 40 mg per day (two 20 mg tadalafil tablets).
For individuals with kidney or liver conditions, the doctor may adjust the starting dose to 10 mg or 20 mg.

How Long Does Tadalafil Last?

The onset of tadalafil usually takes 30-60 minutes. But the peak effectiveness is reached in 2 hours and can last up to 36 hours.
The effects of tadalafil can last up to 36 hours, making it a preferred choice for many users compared to other ED treatments. However, always follow your prescribed tadalafil dosage to avoid complications.
The maximum recommended dose is 20 mg once daily for ED. Taking more than this increases the risk of severe side effects.

FAQs

Q1: How long does tadalafil last?

A: Tadalafil’s effects can last up to 36 hours, making it a popular choice over other ED medications.

Q2: What is tadalafil used for?

A: It is primarily used for erectile dysfunction, BPH, and pulmonary arterial hypertension.

Q3: Is tadalafil safe for daily use?

A: Yes, tadalafil 5 mg is commonly prescribed for daily use, especially for BPH and mild ED.

Q4: Can I take tadalafil with other medications?

A: Avoid combining it with nitrates, alpha-blockers, and some antibiotics, as it can cause dangerous interactions. Always consult your doctor before starting a dosage.

Disclaimer

This content is for informational purposes only and should not replace professional medical advice. Always consult a healthcare provider before starting any new medication.

References

Common questions

Is a generic the same as the brand I was prescribed?

A generic contains the same active molecule at the same strength as the originator brand and must meet the same pharmacopoeial standards. What differs is the name on the carton, the excipients used for coating, and the price.

Do I need a prescription to order?

For every prescription-only molecule, yes. You can upload a photograph of the prescription from your account, and our pharmacist or the processing pharmacy may contact the prescriber to verify it before the order is dispensed.

Why are several brands listed for one molecule?

Manufacturers each market their own brand of the same molecule. Listing them together lets you compare price, pack size and maker rather than being locked into one label.

What if my exact strength is not listed?

The molecule page shows the nearest available strengths of the same ingredient and marks them as such. Never split or combine tablets to reach your dose without asking your doctor first.